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Arginine-deficiency impairs insulin production, glucose production, and liver lipid metabolism. Conditional deficiencies of arginine or ornithine are associated with the presence of excessive ammonia in the blood, excessive lysine, rapid growth, pregnancy, trauma, or protein deficiency and malnutrition. Arginine-deficiency is also associated with rash, hair loss and hair breakage, poor wound healing, constipation, fatty liver, hepatic cirrhosis, and hepatic coma. Lack of arginine reduces the sex impulse and can cause impotence. A
prolonged deficiency is not only harmful to the immunological system
but can also result in disordered carbohydrate metabolism.
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