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Standardized Terminalia chebula is
an exciting new source of both Ellagic Acid and various tannins.
Used for centuries in Asia, extracts
from this fruit have hundreds of clinical studies showing its efficacy.
Name: HARAD
Botanical Name: Terminalia chebula
Local Names: Haritaki (Sanskrit and Bengali),
Harad (Hindi), Karkchettu (Telugu), Kadukkaya (Tamil),
Harade (Marathi) and Gujarati).
Various extracts have
been prepared from the powdered fruits. It contains a constituent which
has a wide anti- bacterial and antifungal spectrum, and also inhibits
growth of E. coli, the most common organism responsible for urinary tract
infection.
The plant is used
extensively in the preparation of many ayurvedic formulations for
infectious diseases such as: chronic ulcers, leucorrhoea, pyorrhoea and fungal infections of the skin.
Triphala is an important
formulation in the ayurvedic pharmacopoeia containing haritaki.
They are used to prevent
aging and impart longevity, immunity and body resistance against disease.
They have beneficial
effects on all the tissues.
Emblica officinalis, Terminalia chebula, Terminalia
belerica, Plumbago zeylanica & Holarrhena antidysenterica were the most
potent anti-bacterials of 82 plants tested
Ahmad 1998
Anti-fungal activity of Terminalia chebula, Punica
granatum, Delonix regia and Emblica officinalis extracts
Dutta 1998
Tannin fraction of T. chebula fruit decreased chemically
induced mutations in Salmonella
Kaur 1998
Bioactivity-guided fractionation of T bellerica fruit
extract led to compounds which bind cholecystokinin and GABA receptors,
and B3EA-6, which binds Neurokinin receptor
Misra 1998
Cassia fistula, Terminalia arjuna and Vitex negundo had
the best antibacterial activity of 34 plants tested
Perumal 1998
Gallic acid & chebulagic acid from T. chebula fruit (kashi,
myrobalans) inhibits cytotoxic T lymphocyte-mediated cytotoxicity, with
IC50 of 30 microM
Hamada 1997
T. spinosa stembark is active against malarial
Plasmodium with IC50 ~10 microgm/ml
Omulokoli 1997
Gallic acid & its ethyl ester from T. chebula fruit
ethanol extract are actaive against methicillin-resistant strains of
Staphylococcus aureus
Sato 1997
Bioactivity-guided fractionation of an extract of
Terminalia bellerica fruit rind led to lignans termilignan &
thannilignan, as well as 7-hydroxy-3',4'-(methylenedioxy)flavan &
anolignan B; all of which were antimicrobial
Valsaraj 1997
T. spinosa twig extract is antibiotic against
Helicobacter pylori with an MIC50 of 125 micrograms/ml
Fabry 1996
T. spinosa twig extract is antifungal against Candida &
Aspergillus
Fabry 1996
Bauhinia, Carissa, Milletia, Mallotus, Rumex, Streblus,
Terminalia & Tridax methanol extracts were antiviral against herpes,
Sindbis & polio viruses
Taylor 1996
Cytomegalovirus is inhibited by Geum japonicum, Syzygium
aromaticum, Terminalia chebula or Rhus javanica hot water extracts
Yukawa 1996
T. avicennoides was the best of 7 plants against Vibrio
cholerae
Akinsinde 1995
T glaucescens was the best antibacterial out of 8
Nigerian tooth cleaning plants
Sote 1995
T. chebula extracts are antibiotic against Salmonella &
Shigella
Phadke 1989
100% kill of Biomphalaria snails by Terminalia
kilimandscharica leaves
Kloos 1987
"Effect of tannins from Terminalia chebula Retz. on the
infectivity of potato virus X " (no abstract)
Verma 1970
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